The Detroit Lions will conclude their preseason scheduled as they travel to play the Buffalo Bills in an NFL pro football exhibition game on Thursday night. <br /><br />Kick off time from Buffalo is set for 7PM Eastern Time with live television coverage available only in the Detroit and Buffalo markets. <br /><br />The NFL odds from this preseason week four game have the road side Detroit Lions favored by -4 ½ points with an over under line set at 40 points. A money line play on the Detroit Lions will return -220 odds with the take back on the Buffalo Bills at +180 odds.
