ROUGH CUT (NO REPORTER NARRATION)<br/> <br />U.S. President Barack Obama announced his nomination for U.S. Health and Human Services Secretary during a news conference at the White House on Friday (April 11).<br/> <br />Sylvia Mathews Burwell, currently the budget director, will replace Kathleen Sebelius if confirmed by the Senate.<br/> <br />Sebelius is resigning from her post after overseeing the botched rollout of President Barack Obama's signature healthcare law. Obama thanked Sebelius for her service and contribution to Obamacare, and welcomed Burwell, as the two woman stood on either side of him.<br/> <br />During her speech, Sebelius said working on the Affordable Care Act was the cause of her life.<br/> <br />"I got to be a leader of H.H.S. during these most historic times. We are on the front lines of a long overdue national change - fixing a broken health system. Now, this is the most meaningful work I've ever been a part of," she said.<br/> <br />Burwell said she was looking forward to taking on the cha