Convicted murder conspirator Kelly Renee Gissendaner was put to death by lethal injection at 12:21 a.m. Wednesday, despite a flurry of last-ditch efforts to stay the execution.<br />Lawyers for the only woman on Georgia’s death row filed multiple appeals with high courts of both the United States and the state of Georgia.<br />Gissendaner, 47 and a mother of three, was scheduled to die by lethal injection at 7 p.m. ET Tuesday evening for her role in the 1997 murder of her husband, Douglas Gissendaner.<br />Prosecutors said Kelly Gissendaner conspired with her lover, Gregory Owen, who stabbed Douglas Gissendaner to death.<br />Owen, who took a plea deal and testified against Gissendaner, is serving life in prison and will become eligible for parole in 2022.<br />Gissendaner was the only woman on death row in Georgia and the first to be executed in the state in 70 years.