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Researchers develop atopic dermatitis treatment using DNA nanoparticles

2018-10-10 1 Dailymotion

The options for treating atopic dermatitis are limited and can have potentially severe side effects.<br />Now, Korean researchers have developed a way to treat the condition using DNA nanoparticles.<br />Park Se-young has more. <br /> Atopic dermatitis, the most common form of eczema, is caused by imbalances in the immune system.<br />Because there is no fundamental treatment for it, doctors usually prescribe steroids to reduce inflammation.<br />But these steroids can have side effects so they are not suitable for extended periods of use.<br />Now, Korean researchers have developed a way to treat atopic dermatitis using DNA nanoparticles.<br /> They created nano-sized X-shaped DNA that can be absorbed by the skin and induce an immune response, which reduces inflammation and helps balance immune functions. <br /><br /> "When the X-shaped DNA was applied, the inflammation-inducing Th2 cytokines were reduced and Th1 cytokines were activated to strengthen immunity."<br /><br />When the DNA nanoparticles were applied to mice with severe atopic dermatitis every day for three weeks, their symptoms were reduced to normal.<br /><br /> "It can be applied to the skin and it did not show side effects or toxicity during animal testing. Since we have domestic and foreign patents, there are possibilities for commercialization."<br /><br /> The DNA nanoparticles can also be used as an ingredient of functional cosmetics.<br />Park Se-young, Arirang News. <br />

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