Men have a higher incidence of most cancers than women. A study showed that the cause could be underlying biological sex differences rather than behavioural differences related to smoking, alcohol consumption, food, and other things. <br />The findings of the research were published by Wiley in Cancer, a peer-reviewed journal of the American Cancer Society.<br />Understanding the reasons for sex differences in cancer risk could provide important information to improve prevention and treatment. Men had an increased risk of most cancers even after adjusting for a wide range of risk behaviors and carcinogenic exposures. Indeed, differences in risk behaviors and carcinogenic exposures between the sexes only accounted for a modest proportion of the male predominance of most cancers (ranging from 11 per cent for esophageal cancer to 50 per cent for lung cancer). <br />The findings suggest that biological differences between sexes such as physiological, immunological, genetic, and other differences play a major role in the cancer susceptibility of men versus women.<br />