Police have launched a murder investigation after a man died in a devastating house fire which also left four others injured - including a teen fighting for his life.<br /> <br />Emergency services were called to Plascom Road, in Wolverhampton, after the blaze broke out at around 1.10am this morning (Tue).<br /><br />More than 20 firefighters battled the flames while five people were rescued from the semi-detached property and rushed to hospital after receiving CPR at the scene. <br /> <br />Police have confirmed a 26-year-old man died in hospital this morning while a 16-year-old boy is in a life-threatening condition. <br /><br />A 52-year-old woman has suffered "life-changing burns" while two other men, aged in their 50s and 20s, have been discharged following treatment.<br /><br />West Midlands Police said a murder probe has now been launched into the "tragic incident" and urged any witnesses to get in touch.<br /><br />Superintendent Martin Hurcomb, of Wolverhampton Police, said: “This is a tragic incident which has resulted in one person losing their life, and four others being hurt.<br /><br />“We’re working flat out to understand what happened and why, and who was responsible.<br /><br />“Forensic experts are examining the scene and the cordon is expected to remain in place for the rest of the day.<br /><br />“Officers will be in the area over the coming days to offer reassurance, while detectives are also in the area to speak to witnesses and gather CCTV.”<br /><br />West Midlands Ambulance Service said paramedics found a man and woman in a critical condition before they were taken to Queen Elizabeth Hospital, in Birmingham.<br /><br />A service spokesman said: "We were called to reports of a property fire on Plascom Road at 1.09am.<br /><br />"Four ambulances, two paramedic officers, a MERIT trauma doctor and the Midlands Air Ambulance critical care car attended the scene.<br /><br />"On arrival we discovered five patients, two of whom, a man and a woman were found in a critical condition.<br /><br />"They received specialist trauma care at the scene before being transported to Queen Elizabeth Hospital, Birmingham.<br /><br />"A teenage male was treated for serious injuries, before being taken to the same hospital. <br /><br />"Two further adult males were treated for minor injuries before being taken to Walsall Manor Hospital."<br /><br />A West Midlands Fire Service spokesman said: "At 01.07am on June 25, we were alerted to a property fire on Plascom Road, Bilston, Wolverhampton.<br /><br />"A total of five fire crews, made up of four fire engines and a 4×4 brigade response vehicle responded, with the first arriving in under five minutes.<br /><br />"The incident involves a fire in a semi-detached house.<br /><br />"Our fire service crews, using breathing apparatus, tackled the blaze with two hose reel jets.<br /><br />"West Midlands Police and West Midlands Ambulance teams are also at the scene supporting our crews."<br /><br />Anyone with information is asked to contact the force via Live Chat online or call 101, quoting log 218 of June 25.