Signs and symptoms of chronic kidney disease develop over time if kidney damage progresses slowly. Loss of kidney function can cause a buildup of fluid or body waste or electrolyte problems. Depending on how severe it is, loss of kidney function can cause:<br />Nausea<br />Vomiting<br />Loss of appetite<br />Fatigue and weakness<br />Sleep problems<br />Urinating more or less<br />Decreased mental sharpness<br />Muscle cramps<br />Swelling of feet and ankles<br />Dry, itchy skin<br />High blood pressure (hypertension) that's difficult to control<br />Shortness of breath, if fluid builds up in the lungs<br />Chest pain, if fluid builds up around the lining of the heart<br />Signs and symptoms of kidney disease are often nonspecific. This means they can also be caused by other illnesses. Because your kidneys are able to make up for lost function, you might not develop signs and symptoms until irreversible damage has occurred.<br />
