Uncover the future of aging with Loyal, the biotech company leading a quiet revolution. Led by founder Celine Halioua, Loyal is unravelling the fundamental mechanisms of pathological aging in our beloved companions.<br />Their mission? To extend the healthy lives of dogs and, in doing so, reveal unprecedented insights into human longevity.<br /><br />Loyal joins the 2025 Forbes Next Billion-Dollar Startups list and involves the largest animal clinical trial ever conducted, enrolling 1,300 dogs across 70 veterinary clinics nationwide. The goal: to give dogs "one healthier year" and yield a "gold mine of data" that will fundamentally advance the understanding of aging in both canines and humans.<br /><br />Could the secret to a longer, healthier human lifespan be found in the journey of our canine companions? Loyal's unofficial slogan hints at the profound answer: "save the dogs, save the world".<br /><br />Read the full story on Forbes: https://www.forbes.com/sites/amyfeldman/2025/08/11/longer-leash-on-life-inside-the-dog-longevity-startup-loyal/<br /><br />Subscribe to FORBES: https://www.youtube.com/user/Forbes?sub_confirmation=1<br /><br />0:00 - Introduction: Can We Delay Aging in Dogs?<br />0:43 - Our Two Approaches to Longevity<br />1:15 - The Science: Keeping the 'Engine' Clean<br />2:05 - Why We Focus on Foundational Biology<br />2:48 - Inside the Largest Clinical Trial in Animal Health<br />3:34 - Why We Test on 'Real World' Dogs, Not Just 'Bougie' Ones<br />4:44 - Overcoming Skepticism in a 'Woo-Woo' Field<br />5:29 - Meet the Founder: Celine Halioua<br />6:58 - The Turning Point: From Art Major to a Mission to Prevent Disease<br />8:16 - The Serendipitous Path to Founding Loyal<br />10:24 - The 'Eating Glass' Reality of Building a Company<br />11:32 - Our Breakthrough: Getting the FDA to Recognize Longevity<br />12:44 - The Investor's 'Aha!' Moment<br />13:46 - The Ultimate Goal: From Dog Longevity to Human Longevity<br /><br />Fuel your success with Forbes. Gain unlimited access to premium journalism, including breaking news, groundbreaking in-depth reported stories, daily digests and more. Plus, members get a front-row seat at members-only events with leading thinkers and doers, access to premium video that can help you get ahead, an ad-light experience, early access to select products including NFT drops and more:<br /><br />https://account.forbes.com/membership/?utm_source=youtube&utm_medium=display&utm_campaign=growth_non-sub_paid_subscribe_ytdescript<br /><br />Stay Connected<br />Forbes newsletters: https://newsletters.editorial.forbes.com<br />Forbes on Facebook: http://fb.com/forbes<br />Forbes Video on Twitter: http://www.twitter.com/forbes<br />Forbes Video on Instagram: http://instagram.com/forbes<br />More From Forbes: http://forbes.com<br /><br />Forbes covers the intersection of entrepreneurship, wealth, technology, business and lifestyle with a focus on people and success.
